Comparison outcome of freash and vitrified donor oocytes in an egg-sharing donation program
Tuesday, 28 June 2011
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Type: Articles
Healthcare Provider: Pedieos IVF Centre
Objective: To compare the survivale, fertilization, early embryonic development, and clinical outcomes from fresh and vitrified cohort oocytes
Design: Review of egg-sharing program, in which the eggs from one donor were shared by recipients of fresh and vitrified eggs.
Setting: IVF center
Patients(s): 77 women, compriising 36 patients receiving vitrified donor oocytes and 41 patients receiving fresh donor oocytes
Intervention(s): Shared donor eggs vitrified by the Cryotop method warmed after vitrifcation, with microinjection of surviving metaphase 2 (MII) or fresh oocytes.
Main Outcome Meaure(s): Survival, fertilization, cleavage rate, pregnancy rate, and implantation.
Result(s): Of the vitrified oocytes, 192 (91.4%) survived. There was no statistically significant difference in fertilization and cleavage rates, embryo quality, or clinical results obtained from vitrified compared with fresh oocytes. The outcomes of cycles using fresh oocytes were predictive of the cycle outcomes after warming of oocytes from the same cohort.
Conclusions: Oocyte donations using vitrified oocytes can provide the same quality of embryos, pregnancy, and implantation potential as fresh oocye donations.
Copyright © 2011 American Society for Reproductive Medicine Published by Elsevier Inc.
For a full version of the scientific report please visit:
http://www.fertstert.org/article/S0015-0282%2811%2900333-5/abstract
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